Did you know? Systemic mastocytosis was first report in 1949
Mastocytosis is Considered to be an Orphan Disease, Affecting 200,000 or Fewer People in the United States
Mastocytosis is an uncommon accumulation of mast cells in the skin and other parts of the body that can cause itching, pain and other symptoms. Learn more below about this rare condition, symptoms and treatment.
01 | Types and Causes
There are two main types of Mastocytosis:
02 | Symptoms and Diagnosis
The symptoms of Cutaneous Mastocytosis are restricted to the skin and range from mild skin rash to more severe symptoms including blistering, hypotension, gastrointestinal bleeding and anaphylactic shock.
In cases of Systemic Mastocytosis, patients may present with a number of symptoms including enlarged liver or spleen, organ function impairment and musculoskeletal pain.
Diagnosis is dependent on what the indicators are present and may include the following:
03 | Treatment
Cutaneous Mastocytosis is usually treated with antihistamines and resolves with no other treatment necessary. There is no cure Systemic Mastocytosis; however, the disease can be controlled with H1 and H2 blockers to relieve itching and reduce gastric acid production. In aggressive cases, interferon-alpha may be injected under the skin to reduce effects on bone marrow.
For more information, please visit: http://www.aaaai.org/conditions-and-treatments/related-conditions/systemic-mastocytosis